Dr. Oliver Thorn-Seshold
Chemical Biology and Pharmaceutical Chemistry

	Address	Department of Pharmacy Ludwig-Maximilians-Universität München Butenandtstr. 5-13 81377 München Germany
	Phone	+49 (0)89 2180-77246
	Room-Nr.	C1.059
	Email
	Home page	thornseshold.cup.uni-muenchen.de

Research Interests

• Chemical Biology
• Photopharmacology
• Targeted Cytotoxins in Cancer Therapy

Short CV

• Since 2018: DFG Emmy Noether independent group leader
• Since 2016: Independent Research, LMU Munich
• 2013-2016: Postdoctoral Research, LMU Munich (Prof. Dirk Trauner)
• 2009-2013: PhD in Chemical Biology at the Ecole Normale Superieure de Lyon (Prof. Jens Hasserodt)
• 2004-2009: BSc in Organic Chemistry at the University of Sydney and MSc in Bioorganic Chemistry at the Ecole Normale Superieure de Lyon

Key publications

• A Sailer, et al., O Thorn-Seshold*. Hemithioindigos for cellular photopharmacology: desymmetrised molecular switch scaffolds enabling design control over the isomer-dependency of potent antimitotic bioactivity. ChemBioChem 2019, article ASAP (in press).
• A Singh, et al. Polarized microtubule dynamics directs cell mechanics and coordinates forces during epithelial morphogenesis. Nature Cell Biology 2018, 1126.
• J Zenker, et al. A Microtubule Organizing Center Directing Intracellular Transport in the Early Mouse Embryo. Science 2017, 925.
• M Borowiak, et al., D Trauner*, O Thorn-Seshold*. Photoswitchable Inhibitors of Microtubule Dynamics Optically Control Mitosis and Cell Death. Cell 2015, 162, 403.
• O Thorn-Seshold* et al. Azoaryls as Reversibly Modulatable Tubulin Inhibitors. WO2015166295, 2014.