Title: Self-healing dyes – new promise in live cell imaging
Abstract:
Phototoxicity and photobleaching have become prevailing issues in the advanced imaging era when boosted illumination is applied, compromising both the acquisition window and the physiological relevance of the recorded data. We advocate leveraging chemical approaches to tackle phototoxicity and photobleaching. I will introduce our recent work on exploiting phenyloxadiazole (POD)-based chemistry to label cysteine which alleviate photobleaching, and discuss the new and general applications of cyclooctatetraene (COT) -conjugated cyanine dyes in time-lapse live cell imaging. For example, we present PK Mito Orange probe, a mitochondrial inner membrane stain that enables 30 frames of STED recording and multi-color imaging of mitochondrial components.
Vortrag,
Prof. Trapp, OC 11:00, Baeyer-Hörsaal
Merck-Banyu Lectureship Award 2021 und 2022
Prof. Dr. Masakazu NAMBO, Institute of Transformative Bio-Molecules, Nagoya University, Japan (winner 2021) New Transformations of Organosulfones through C–SO2 Bond Activation
Prof. Dr. Kenzo YAMATSUGU, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Japan (winner 2022) Chemical Catalysis Enabling Synthetic Intervention in Cellular Epigenome
jointly organized by the Ludwig Maximilian University of Munich and Merck Life Science KGaA with the collaboration of the MChG
08:30 - 09:00: Registration
09:00 - 09:20: Welcome by Merck KGaA, Anja Hoffmann-Röder (LMU) and Dominik Leitz (MChG)
09:20 - 10:15: Lecture - Dr. Kenneth Schwieter - Head of Product Marketing, Chemical Synthesis and Discovery Chemistry - Merck KGaA - "New Tools for Chemical Synthesis"
10:15 - 10:45: Coffee break
10:45 - 11:40: Lecture - Prof. Adriaan J. Minnaard - Stratingh Institute of Chemistry - University of Groningen - "Synthesis-driven natural product chemistry"
11:40 - 12:15: European Retrosynthesis Competition Prize ceremony and winner's lecture
12:15 - 15:00: Lunch break and poster session
15:00 - 15:35: Lecture - Dr. Golo Storch - Department of Chemistry - Technical University of Munich - "Flavin catalysis as a versatile tool in synthetic organic chemistry"
15:35 - 16:10: Lecture - Dr. Fumito Saito - Department of Chemistry - Ludwig Maximilian University Munich - "One-step, three-component synthesis of sulfur functional groups"
16:10 - 17:10: Lecture - Prof. Paul Knochel - Department of Chemistry - Ludwig Maximilian University Munich - "Li, Na, Mg and Zn-organometallics for organic synthesis"
Thu, Oct 12, 2023
IMPRS Lecture Series,
MPI of Biochemistry 17:00, Martinsried T-Building, Large Lecture Hall
Prof. Dietmar Trenk
(FESCK Klinische Pharmakologie, Klinik für Kardiologie und Angiologie Universitätsklinikum Freiburg, Universitäts-Herzzentrum Bad Krozingen)
Chronische Herzinsuffizienz - Therapie im Umbruch
Thu, Nov 23, 2023
IMPRS Lecture Series,
MPI of Biochemistry 17:00, Martinsried T-Building, Large Lecture Hall
Richard Merrill, LMU
Adaptive introgression of a visual preference gene
Festveranstaltung zur Überreichung der Master-Zeugnisse in Chemie und Biochemie sowie der Römer-Preise 2023
15:15 Uhr Festveranstaltung zur Überreichung der Master-Zeugnisse in Chemie und Biochemie sowie der Römer-Preise 2023
17:00 Uhr Römer-Lecture: Chaperone in der Zelle: Die Rolle bei Gesundheit und Krankheit;
Prof. Dr. Ulrich Hartl, Max-Planck-Insitut für Biochemie, Abt. Zelluläre Biochemie
Mon, Dec 04, 2023
Symposium,
SFB 1309 09:00, Building L, conference room (L00.010)
Prof. Petra Staubach-Renz
(Managing Director Clinical Research Center Dermatologie und Allergie, Hautklinik und Poliklinik der Universitätsmedizin Johannes Gutenberg-Universität Mainz)
Atopische Dermatitis und andere entzündliche Hauterkrankungen – Update 2024
Thu, Jan 11, 2024
IMPRS Lecture Series,
MPI of Biochemistry 17:00, Martinsried T-Building, Large Lecture Hall
Benedikt Grothe, LMU
Neural principles of encoding and decoding of auditory space