Mayr's Database Of Reactivity Parameters
AK Prof. Mayr

Details of Molecule trifluoroethanol

For reactivities of structurally related compounds go to: Nucleophiles » O-Nucleophiles » Alcohols and aqueous solvents » Other solvents (pure or mixtures)
Structure image of molecule
Molecule class Nucleophiles » O-Nucleophiles » Alcohols and aqueous solvents » Other solvents (pure or mixtures)
Quality ***
Parameters N  Parameter: 1.11
sN Parameter: 0.96
Comment

Solvent nucleophilicity parameters N and sN were determined with reference electrophiles and correspond to first-order rate constants. Previously published reactivity parameters have been revised (N = 1.23, sN = 0.92, J. Am. Chem. Soc. 2004, 126, 5174-5178).

Sum formula C2H3F3O
Solvent TFE
Reference J. Am. Chem. Soc. 2012, 134, 13902-13911
DOI: 10.1021/ja306522b